September 28, 2008Robert Nowinski – Publications in Human Infectious Diseases1. Stephens, R.S., Tam, M.R., Kuo, C., and Nowinski, Robert. Monoclonal antibodies to Chlamydia Trachomatis: Antibody specificities and antigen characterization. J. Immunology 128:1083-1089, 1982.
2. Tam, M.R., Buchanan, T.M., Sandstrom, E.G., Holmes, K.K., Knapp, J.S., Siadak, A.W., and Nowinski, Robert. Serological classification of Neisseria gonorrhoeae with monoclonal antibodies. Infection and Immunity 36:1042-1053, 1982.
3. Goldstein, L.C., McDougall, J., Hackman, R., Meyers, J.D., Thomas, E.D., and Nowinski, Robert. Monoclonal antibodies to cytomegalovirus (CMV): Rapid identification of clinical isolates and preliminary use in diagnosis of CMV pneumonia. Infection and Immunity 38:273-281, 1982.
4. Stephens, R.S., Kuo, C.-C., Tam, M.R., and Nowinski, Robert. Monoclonal antibodies to Chlamydia trachomatis. In, Chlamydia Infections, Mardh, P.A. et al., eds., Elsevier Biomedical Press, Amsterdam, pp. 329-332, 1982.
5. Tam, M.R., Stephens, R.S., Kuo, C.-C., Holmes, K.K., Stamm, W.E., and Nowinski, Robert. Use of monoclonal antibodies to Chlamydia trachomatis as immunodiagnostic reagents. In, Chlamydial Infections, Mardh, P.A., et al., eds., Elsevier Biomedical Press, Amsterdam, pp. 317-320, 1982.
6. Nowinski, Robert, Tam, M.R., Goldstein, L.C., Stong, L., Kuo, C.-C., Corey, L., Stamm, W.E., Handsfield, H.H., Knapp, J.S., and Holmes, K.K. Monoclonal antibodies for the diagnosis of infectious diseases in humans. Science 219:637-644, 1983.
7. Goldstein, L.C., Corey, L., McDougall, J.K., Tolentino, E., and Nowinski, Robert. Monoclonal antibodies to herpes simplex viruses: Use in antigenic typing and rapid diagnosis. J. Infectious Diseases 147:829-837, 1983.
8. Peterson, E., Schmidt, O.W., Goldstein, L.C., Nowinski, Robert, and Corey, L. Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: Comparison with type-specific rabbit antisera and restriction endonuclease analysis of viral DNA. J. Clin. Microbiol. 17:92-96, 1984.
9. Tam, M.R., Stamm, W.E., Handsfield, H.H., Stephens, R., Kuo, C.-C., Holmes, K.K., Ditzenberger, K., Krieger, M., and Nowinski, Robert. Culture-independent diagnosis of Chlamydia trachomatis using monoclonal antibodies. N. Eng. J. of Med. 310:1146-1150, 1984.
10. Knapp, J.S., Tam, M.R., Nowinski, Robert, Holmes, K.K., and Sandstrom, E.G. Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. J. Infect. Diseases 150:44-48, 1984.
11. Tam, M.R., Goldstein, L.C., and Nowinski, Robert. Monoclonal antibodies for the diagnosis of chlamydial, gonococcal, and herpesvirus infection. In, Biotechnology Handbook, Cheremisinoff, P.N., and Ouelette, R.P., eds., Butterworth/Ann Arbor Science Publishers, Ann Arbor, MI, pp. 380-382, 1985.
12. Lukehart, S.A., Tam, M.R., Hom, J., Baker-Zander, S.A., Holmes, K.K., and Nowinski, Robert. Characterization of monoclonal antibodies to Treponema Pallidum. J. Immunol. 134:585-592, 1985.
13. Goldstein, L.C., Tam, M.R., Allen, J.D., and Nowinski, Robert. Diagnosis of sexually transmitted diseases with monoclonal antibodies. In, Proceedings of the International Symposium on Medical Virology, Elsevier Science Publishing Company, New York and Copenhagen, 1986.
14. Goldstein, L.C. and Nowinski, Robert. Diagnosis of herpesviruses with monoclonal antibodies. In, Human Herpesvirus Infections, Lopez, C. and Roizman, B., eds., Raven Press, New York, pp. 195-202, 1986.
15. Goldstein, L.C., Tam, M.R., and Nowinski, Robert. Role of monoclonal antibodies in detection of microbial antigens. In, Microbial Antigenodiagnosis, K. Wicher, ed., CRC Press, Boca Raton, FL, pp. 201-218, 1987.
16. Challoner, Peter B., Smith, Kirsten T., Parker, Jay D., MacLeod, David L., Coulter, Silvia N., Rose, Timothy M., Schultz, Emily R., Bennett, Lindsey, Garber, Richard L., Chang, Ming, Schad, Peter A., Stewart, Patricia M., Nowinski, Robert, Brown, Joseph P. and Burmer, Glenna C. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc. Natl. Acad. Sci. USA, 92:7440-7444, 1995.
17. Francis, D.P. and Nowinski, R.C. Vaccine Reactions. Nature Medicine 4:746, 1998.
Robert Nowinski – Publications in Immunology
1. Nowinski, Robert, Boyse, E.A., Old, L.J., and Carswell, E.A. Influence of mammary tumor virus infection on the acceptance or rejection of transplanted ML+ leukemias. Proc. Soc. Exptl. Biol. Med. 127:20-25, 1968.
2. Chang, S., Nowinski, Robert, Nishioka, K., and Irie, R.F. Immunological studies on mouse mammary tumors. IV. Further characterization of a mammary tumor antigen and its distribution in lymphatic cells of allogeneic mice. Int. J. Cancer 9:409-416, 1972.
3. Nowinski, Robert and Peters, E.D. Cell surface antigens associated with murine leukemia virus: Definition of the GL and GT antigenic systems. J. Virology 12:1104-1117, 1973.
4. Nowinski, Robert and Kaehler, S.L. Antibody to leukemia virus: Widespread occurrence in inbred mice. Science 185:869-871, 1974.
5. Nowinski, Robert, Kaehler, S.L., and Burgess, R.R. Immune response of the mouse to endogenous leukemia viruses. Cold Spring Harbor Symposium XXXIX, 1123-1128, 1975.
6. Zarling, J.M., Nowinski, Robert, and Bach, F.H. Lysis of leukemia cells by spleen cells of normal mice. Proc. Natl. Acad. Sci. 72:2780-2784, 1975.
7. Nowinski, Robert and Klein, P.A. Anomalous reactions of mouse alloantisera with cultured tumor cells. II.Cytotoxicity caused by antibodies to leukemia viruses. J. Immunol. 115:1261-1268, 1975.
8. Nowinski, Robert. Immune response to leukemia viruses in mice. In, Viral Immunology and Immunopathology, Notkins, A., Ed., Academic Press, New York, pp. 237-260, 1975.
9. Nowinski, Robert. Genetic control of natural immunity to ecotropic mouse leukemia viruses. II. Immune response genes. Infection and Immunity 13:1098-1102, 1976.
10. Nowinski, Robert and Watson, A. Immune response of the mouse to the major core protein (p30) of ecotropic leukemia viruses. J. Immunology 117:693-696, 1976.
11. Wettstein, P.J., Krammer, R., Nowinski, Robert, David, C.S., Frelinger, J.A., and Schreffler, D.C. A cautionary note regarding Ia and H-2 typing of murine lymphoid tumors. Immunogenetics 3:507-516, 1976.
12. Nowinski, Robert and Doyle, T. Antibody to murine leukemia virus: Genetic control by the Ir-1 locus in PL mice. J. Immunology 117:350-351, 1976.
13. Nowinski, Robert and Baron, J. Genetic and immunological controls of murine leukemia viruses in AKR mice. Third International Symposium on Detection and Prevention of Cancer, pp. 173-198, 1977.
14. Nowinski, Robert and Doyle, T. Decreased immunity to viral antigens and increased expression of endogenous leukemia viruses in athymic (nude) mice. J. Virology 77:429-432, 1977.
15. Ledbetter, J. and Nowinski, Robert. Identification of the G cell surface antigen (GCSA) associated with murine leukemia virus-infected cells. J. Virology 23:315-322, 1977.
16. Nowinski, Robert and Doyle, T. Cellular changes in the thymuses of preleukemic AKR mice: Correlation with changes in the expression of murine leukemia viruses. Cell 12:341-353, 1977.
17. Brown, J.P., Klitzman, J.M., Hellstrom, I., Nowinski, Robert, and Hellstrom, K.E. Antibody response of mice to chemically induced tumors. Proc. Natl. Acad. Sci. 75:955-958, 1978.
18. Boiocchi, M. and Nowinski, Robert. Polymorphism in the major core protein (p30) of murine leukemia viruses as identified by mouse antisera. Virology 84:530-535, 1978.
19. Nowinski, Robert, Emery, S., and Ledbetter, J. Identification of an FMR cell surface antigen associated with murine leukemia virus-infected cells. J. Virology 26:805-812, 1978.
20. Nowinski, Robert, Lostrom, M.E., Tam, M.R., Stone, M.R., and Burnette, W.N. The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses. Virology 93:111-126, 1979.
21. Boiocchi, M. and Nowinski, Robert. Antibodies to the envelope protein (gp70) of endogenous xenotropic and ecotropic leukemia viruses: Induction by immunization with leukemia cells. Virology 96:281-285, 1979.
22. Stone, M.R., Lostrom, M.E., Tam, M.R., and Nowinski, Robert. Monoclonal mouse antibodies as probes for antigenic polymorphism in murine leukemia viruses. Virology 96:286-290, 1979.
23. Green, W.R., Nowinski, Robert, and Henney, C.S. The generation and specificity of cytotoxic T cells raised against syngeneic tumor cells bearing AKR/Gross murine leukemia virus antigens. J. Exp. Med. 150:51-66, 1979.
24. Lostrom, M.E., Stone, M.R., Tam, M., Burnette, W.N., Pinter, A., and Nowinski, Robert. Monoclonal antibodies against murine leukemia viruses: Identification of six antigenic determinants on the p15(E) and gp70 envelope proteins. Virology 98:336-350, 1979.
25. Brown, J., Boiocchi, M., and Nowinski, Robert. Detection of polymorphism in BALB/c leukemia viruses with mouse antisera. J. Virology 32:345-349, 1979.
26. Pollack, S.B., Tam, M.R., Nowinski, Robert, and Emmons, S.L. Presence of T cell-associated surface antigens on murine NK cells. J. Immunology 123:1818-1821, 1979.
27. Bernstein, I.D., Tam, M.R., and Nowinski, Robert. Mouse leukemia: Therapy with monoclonal antibodies against a thymus differentiation antigen. Science 207:68-71, 1980.
28. Stone, M.R. and Nowinski, Robert. Topological mapping of murine leukemia virus proteins by competition-binding assays with monoclonal antibodies. Virology 100:370-381, 1980.
29. Oroszlan, S. and Nowinski, Robert. Lysis of retroviruses with monoclonal antibodies against viral envelope proteins. Virology 101:296-299, 1980.
30. Bernstein, I.D., Nowinski, Robert, Tam, M.R., McMaster, B., Houston, L.L., and Clark, E.A. Monoclonal Antibody Therapy of Mouse Leukemia, In, Monoclonal Antibodies, Kennett, R.H., McKearn, T.J., and Bechtol, K.B., eds., Plenum Press, pp. 275-291, 1980.
31. Hansen, J.A., Martin, P.J., and Nowinski, Robert. Monoclonal antibodies identifying a novel T cell antigen and Ia antigens of human lymphocytes. Immunogenetics 10:247-260, 1980.
32. Bernstein, I.D., Nowinski, Robert, and Stiefel, J. The role of viral and cell-associated antigens in the cell-mediated immune response of rats to virus-induced lymphoma cells. J. Immunology 124:1727-1732, 1980.
33. Green, W.R., Nowinski, Robert, and Henney, C.S. Specificity of cytolytic T cells directed against AKR/Gross virus-induced syngeneic leukemias: Antibodies directed against H-2K, but not against viral proteins, inhibit lysis. J. Immunology 125:647-655, 1980.
34. Houston, L.L., Nowinski, Robert, and Bernstein, I.D. Specific in vivo localization of monoclonal antibodies directed against the Thy 1.1 antigen. J. Immunology 125:837-843, 1980.
35. Siadak, A.W. and Nowinski, Robert. Identification of Ly-5 and T200 antigens on identical cell surface proteins. J. Immunology 125:1400-1401, 1980.
36. Martin, P.J., Hansen, J.A., Nowinski, Robert, and Brown, M.A. A new human T cell differentiation antigen: Unexpected expression on chronic lymphocytic leukemia cells. Immunogenetics 11:429-439, 1980.
37. Tam, M.R., Green, W.R., and Nowinski, Robert. Cytotoxic activities of monoclonal antibodies against the envelope proteins of murine leukemia virus. Cancer Research 40:3850-3853, 1980.
38. Hansen, J.A., Martin, P.J., Kamoun, M., Torok-Storb, B., Newman, W., Nowinski, Robert, and Thomas, E.D. Monoclonal antibodies recognizing human T cells: Potential role for preventing graft-versus-host reactions following allogeneic marrow transplantation. Transplantation Proceedings 13:1133-1137, 1981.
39. Siadak, A.W. and Nowinski, Robert. Thy-2: A murine thymocyte-brain alloantigen controlled by a gene linked to the major histocompatibility complex. Immunogenetics 12:45-58, 1981.
40. Kamoun, M., Martin, P.J., Hansen, J.A., Brown, M.A., Siadak, A.W., and Nowinski, Robert. Identification of a human T lymphocyte surface protein associated with the E-rosette receptor. J. Exp. Med. 153:207-212, 1981.
41. Martin, P.J., Hansen, J.A., Siadak, A.W., and Nowinski, Robert. Monoclonal antibodies recognizing normal human T lymphocytes and malignant human B lymphocytes: A comparative study. J. Immunology 127:1920-1923, 1981.
42. Houston, L.L. and Nowinski, Robert. Cell-specific cytotoxicity expressed by a conjugate of ricin and murine monoclonal antibody directed against thy 1.1 antigen. Cancer Research, 41:3913-3917, 1981.
43. Bernstein, I.D., Nowinski, Robert, and Wright, P.W. Monoclonal Antibodies: Prospects for Cancer Treatment, In, Immunological Approaches to Cancer Therapeutics, Mihich, E., ed., John Wiley and Sons, Inc., New York, pp. 277-297, 1982.
44. Lane, J., Brown, M., Bernstein, I., Wilcox, P.I., Slichter, S.J., and Nowinski, Robert. Serological and biochemical analysis of the P1A1 alloantigen of human platelets. British Journal of Haematology 50:351-361, 1982.
45. Bernstein, I.D. and Nowinski, Robert. Monoclonal Antibody Treatment of Transplanted and Spontaneous Murine Leukemia, In, Hybridomas in the Diagnosis and Treatment of Cancer, Mitchell, M. and Oettgen, H.F., eds., Raven Press, New York, pp. 97-112, 1982.
46. Tam, M.R., Bernstein, I.D., and Nowinski, Robert. Alteration of lymphoid cells in AKR mice by treatment with monoclonal antibody against Thy 1 antigen. Transplantation 33:269-273, 1982.
47. Nowinski, Robert, Tam, M.R., Goldstein, L.C., Stong, L., Kuo, C.-C., Corey, L., Stamm, W.E., Handsfield, H.H., Knapp, J.S., and Holmes, K.K. Monoclonal antibodies for the diagnosis of infectious diseases in humans. Science 219:637-644, 1983.
48. Auditore-Hargreaves, K., Houghton, R.L., Monji, N., Priest, J.H., Hoffman, A.S., and Nowinski, Robert. Phase separation immunoassays. Clin. Chem. 33:1509-1516, 1987.
49. Monji, N., Cole, C.A., Tam, M., Goldstein, L., and Nowinski, Robert. Application of a thermally-reversible polymer-antibody conjugate in a novel membrana-based immunoassay. Biochemical $ Biophysical Research Communications. 172: 652-660, 1990.
50. Francis, D.P. and Nowinski, Robert. Vaccine Reactions. Nature Medicine 4:746, 1998.
51. Hoffman, A.s., Stayton, P.S., Bulmus, V., Chen G., Shoemaker, S., Yang, H.J., Monji, N., Nowinski, Robert, Cole, C.A., Priest, J.H., Harris, J.M., Nakamae, K., Nishino, T., and Miyata, T. Founder’s Award, Society for Biomaterials. Really smart bioconjugates of smart polymers and receptor proteins. J. Biomed. Materials Research 52:577-586, 2000.